TY - JOUR
T1 - Liposarcoma in adult limbs treated by limb-sparing surgery and adjuvant radiotherapy
AU - Issakov, J.
AU - Soyfer, V.
AU - Kollender, Y.
AU - Bickels, J.
AU - Meller, I.
AU - Merimsky, O.
PY - 2006/12
Y1 - 2006/12
N2 - Between December 1995 and March 2003, 38 adult patients with intermediate or high-grade liposarcoma in a limb were treated by limb-sparing surgery and post-operative radiotherapy. The ten-year local recurrence-free survival was 83%, the ten-year metastasis-free survival 61%, the ten-year disease-free survival 51% and the ten-year overall survival 67%. Analysis of failure and success showed no association with the age of the patients, gender, the location of the primary tumour, the type of liposarcoma and the quality of resection. Our results indicate that liposarcoma may recur even ten years after the end of definitive therapy and may spread to unexpected sites as for soft-tissue sarcoma.
AB - Between December 1995 and March 2003, 38 adult patients with intermediate or high-grade liposarcoma in a limb were treated by limb-sparing surgery and post-operative radiotherapy. The ten-year local recurrence-free survival was 83%, the ten-year metastasis-free survival 61%, the ten-year disease-free survival 51% and the ten-year overall survival 67%. Analysis of failure and success showed no association with the age of the patients, gender, the location of the primary tumour, the type of liposarcoma and the quality of resection. Our results indicate that liposarcoma may recur even ten years after the end of definitive therapy and may spread to unexpected sites as for soft-tissue sarcoma.
UR - http://www.scopus.com/inward/record.url?scp=33845786110&partnerID=8YFLogxK
U2 - 10.1302/0301-620X.88B12.17964
DO - 10.1302/0301-620X.88B12.17964
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AN - SCOPUS:33845786110
SN - 0301-620X
VL - 88
SP - 1647
EP - 1651
JO - Journal of Bone and Joint Surgery - Series B
JF - Journal of Bone and Joint Surgery - Series B
IS - 12
ER -