Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients

A. M.M. Miltenburg, D. Aderka, J. M. van Laar, D. Wallach, F. C. Breedveld

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and-RII were measured by ELISA. We found that sTNF-RI and-RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and-II did not represent markers for local disease activity in arthritis patients.

Original languageEnglish
Pages (from-to)117-119
Number of pages3
JournalRheumatology International
Volume13
Issue number3
DOIs
StatePublished - Aug 1993
Externally publishedYes

Keywords

  • (Rheumatoid) arthritis
  • Joint fluid
  • Soluble TNF receptors

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