Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.
|Number of pages||4|
|Journal||Journal of Cancer Research and Clinical Oncology|
|State||Published - Apr 1981|
- Leukocyte alkaline phosphatase