Leukocyte alkaline phosphatase in cancer patients

N. Walach; S. Kaufman; Y. Horn

doi:10.1007/BF00405903

Leukocyte alkaline phosphatase in cancer patients

N. Walach^*, S. Kaufman, Y. Horn

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.

Original language	English
Pages (from-to)	69-72
Number of pages	4
Journal	Journal of Cancer Research and Clinical Oncology
Volume	100
Issue number	1
DOIs	https://doi.org/10.1007/BF00405903
State	Published - Apr 1981

Keywords

Cancer
Leukocyte alkaline phosphatase
Metastases

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF00405903

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title = "Leukocyte alkaline phosphatase in cancer patients",

abstract = "Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.",

keywords = "Cancer, Leukocyte alkaline phosphatase, Metastases",

author = "N. Walach and S. Kaufman and Y. Horn",

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language = "אנגלית",

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AU - Walach, N.

AU - Kaufman, S.

AU - Horn, Y.

PY - 1981/4

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N2 - Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.

AB - Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.

KW - Cancer

KW - Leukocyte alkaline phosphatase

KW - Metastases

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SN - 0171-5216

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EP - 72

JO - Journal of Cancer Research and Clinical Oncology

JF - Journal of Cancer Research and Clinical Oncology

IS - 1

ER -

Leukocyte alkaline phosphatase in cancer patients

Abstract

Keywords

UN SDGs

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