Leukocyte alkaline phosphatase in cancer patients

N. Walach*, S. Kaufman, Y. Horn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Leukocyte alkaline phosphatase (LAP) activity in peripheral blood was determined in 113 patients with non-metastatic malignancies, 36 patients with metastatic spread, and 22 individuals who served as controls. The LAP score of the non-metastatic cancer patients was significantly higher (p<0.001) than the controls, and the score of the metastatic group was further increased significantly as compared to both control (p<0.001) and nonmetastatic groups (p<0.001). The results of this survey suggest that the level of LAP score in peripheral blood might be used to differentiate between non-metastatic and metastatic disease and might serve as an aid in prognosis of the patients.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalJournal of Cancer Research and Clinical Oncology
Issue number1
StatePublished - Apr 1981


  • Cancer
  • Leukocyte alkaline phosphatase
  • Metastases


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