Leukocyte alkaline phosphatase and carcinoembryonic antigen in breast cancer patients: Clinical correlation with the markers

Natalio Walach*, Amiram Guterman, Jacob L. Zaidman, Suzana Kaufman, Sally Scharf

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Leukocyte alkaline phosphatase (LAP) scores in peripheral blood and plasma carcinoembryonic antigen (CEA) levels were determined in 208 breast cancer patients with nonmetastatic disease. Patients were followed until clinical manifestations of metastases appeared. Then the LAP score and CEA level were analyzed in relation to the clinical appearance of metastases. Of the 208 patients studied, 58 developed metastases during the follow‐up period. The LAP scores and CEA levels of this group of patients were compared to a control group of 60 breast cancer patients who did not develop metastases. Of the two markers, LAP score seems to be considerably more useful in detecting metastatic disease.

Original languageEnglish
Pages (from-to)85-87
Number of pages3
JournalJournal of Surgical Oncology
Volume40
Issue number2
DOIs
StatePublished - Feb 1989

Keywords

  • breast cancer
  • markers
  • metastases

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