LeEIX2 interactors’ analysis and EIX-mediated responses measurement

Meirav Leibman-Markus, Silvia Schuster, Adi Avni*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

24 Scopus citations

Abstract

Plant-pathogen interactions involve a large number of wide regulatory systems, necessary for plant defense responses against pathogen attack. The fungal protein ethylene-inducing xylanase (EIX) elicits defense responses in specific cultivars of tobacco and tomato. The response to EIX is controlled by a single locus encoding for LeEIX2, a leucine-rich-repeat receptor-like-protein (LRR-RLP). As an RLP, LeEIX2 does not possess an obvious cytoplasmic signaling moiety such as a kinase domain. To study LeEIX2 mode of action, it is essential to identify the potential interactors involved after EIX perception. Here, we describe the in vivo co-IP methodology used for protein interaction verification and ethylene and ROS (reactive oxygen species) measurements used for physiological effects assessment.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages167-172
Number of pages6
DOIs
StatePublished - 2017

Publication series

NameMethods in Molecular Biology
Volume1578
ISSN (Print)1064-3745

Keywords

  • Co-IP
  • Defense responses
  • Ethylene-inducing xylanase
  • LRR-RLP
  • MAMP
  • ROS

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