@article{280082ddb60248f6a3826b8208252771,
title = "LeEix1 functions as a decoy receptor to attenuate LeEix2 signaling",
abstract = "The receptors for the fungal elicitor EIX (LeEix1 and LeEix2) belong to a class of leucine-rich repeat cell-surface glycoproteins with a signal for receptor-mediated endocytosis. Both receptors are able to bind the EIX elicitor while only the LeEix2 receptor mediates defense responses. We show that LeEix1 acts as a decoy receptor and attenuates EIX induced internalization and signaling of the LeEix2 receptor. We demonstrate that BAK1 binds LeEix1 but not LeEix2. In plants where BAK1 was silenced, LeEix1 was no longer able to attenuate plant responses to EIX, indicating that BAK1 is required for this attenuation. We suggest that LeEix1 functions as a decoy receptor for LeEix2, a function which requires the kinase activity of BAK1.",
keywords = "Bak1, Decoy receptor, Endocytosis, LRR-RLP, LeEix",
author = "Maya Bar and Miya Sharfman and Adi Avni",
note = "Funding Information: This work was partly supported by the Israel Science Foundation administered by the Israel Academy of Science and Humanities no. 294/07. FYVE-dsRed was a kind gift from Dr. Jozef Samaj. We thank Dr. Russinova and Dr. de Vries for the Arabidopsis BAK1. Dr. Rathjen for BAK1 VIGS vectors and Dr. Jia Li for BAK1 K317E.",
year = "2011",
month = mar,
doi = "10.4161/psb.6.3.14714",
language = "אנגלית",
volume = "6",
pages = "455--457",
journal = "Plant Signaling and Behavior",
issn = "1559-2316",
publisher = "Taylor and Francis Ltd.",
number = "3",
}