Latent inhibition as a function of schizotypality and gender: Implications for schizophrenia

R. E. Lubow*, Gonzalo De La Casa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


In three within-subject experiments, we demonstrated that preexposure to an irrelevant stimulus interfered with performance when that stimulus subsequently predicted the correct location of a target stimulus. This latent inhibition-like effect (LI) was manifest in response time measures, but not errors. As with other related paradigms, LI was a function of an interaction between schizotypy-level and gender. Low schizotypal females and high schizotypal males exhibited significant LI, while high schizotypal females and low schizotypal males failed to produce LI effects. The results, similar to findings with schizophrenic patients, suggest a sexual dimorphism of cognitive dysfunction in schizophrenia, particularly in regard to the processing of irrelevant stimuli.

Original languageEnglish
Pages (from-to)69-86
Number of pages18
JournalBiological Psychology
Issue number1
StatePublished - 2002


FundersFunder number
Spanish governmentBSO2000-0323-C02-01
Israel Academy of Sciences and Humanities
Israel Science Foundation


    • Attention
    • Gender
    • Latent inhibition
    • Schizophrenia
    • Schizotypy


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