TY - JOUR
T1 - Latent inhibition and asymmetrical visual-spatial attention in children with ADHD
AU - Lubow, R. E.
AU - Braunstein-Bercovitz, Hedva
AU - Blumenthal, Orit
AU - Kaplan, Oren
AU - Toren, Paz
N1 - Funding Information:
The writing of this paper was supported by a grant to R.E.L. from The Israel Science Foundation funded by the Israel Academy of Sciences and Humanities (932/02-1). The authors thank Ina Weiner for helpful comments on an earlier draft of this article.
PY - 2005/10
Y1 - 2005/10
N2 - The research was designed to determine whether the purported hemispheric asymmetries that are associated with attention deficit/hyperactivity disorder (ADHD) affect performance on a selective attention visual search task, and whether any obtained asymmetry will be modulated by methylphenidate. Two groups of children (8-15 years) with ADHD, one with methylphenidate treatment (ADHD+) and one without (ADHD-), were compared to matched controls on a two-stage visual search task. The task assessed right-left visual field asymmetries and the effects of changing a previous distractor into a target. Such a procedure, related to latent inhibition (LI; poorer performance to a previously irrelevant stimulus than to a novel one), can provide evidence for dysfunctional processing of irrelevant stimuli. All three groups exhibited the LI effect. The ADHD group, however, exhibited less LI for left- than right-side targets, an effect absent in the control and ADHD+ groups, suggesting a lateralized attentional deficit for ADHD-that was normalized by methylphenidate.
AB - The research was designed to determine whether the purported hemispheric asymmetries that are associated with attention deficit/hyperactivity disorder (ADHD) affect performance on a selective attention visual search task, and whether any obtained asymmetry will be modulated by methylphenidate. Two groups of children (8-15 years) with ADHD, one with methylphenidate treatment (ADHD+) and one without (ADHD-), were compared to matched controls on a two-stage visual search task. The task assessed right-left visual field asymmetries and the effects of changing a previous distractor into a target. Such a procedure, related to latent inhibition (LI; poorer performance to a previously irrelevant stimulus than to a novel one), can provide evidence for dysfunctional processing of irrelevant stimuli. All three groups exhibited the LI effect. The ADHD group, however, exhibited less LI for left- than right-side targets, an effect absent in the control and ADHD+ groups, suggesting a lateralized attentional deficit for ADHD-that was normalized by methylphenidate.
KW - Attention deficit/hyperactivity disorder (ADHD)
KW - Hemisphericity
KW - Latent inhibition
KW - Methylphenidate
KW - Visual search
UR - http://www.scopus.com/inward/record.url?scp=27344459339&partnerID=8YFLogxK
U2 - 10.1080/09297040590951578
DO - 10.1080/09297040590951578
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:27344459339
SN - 0929-7049
VL - 11
SP - 445
EP - 457
JO - Child Neuropsychology
JF - Child Neuropsychology
IS - 5
ER -
