Late relapse of testis cancer

Yaron Ehrlich*, Eli Rosenbaum, Jack Baniel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Most relapses of germ-cell tumors occur within 2 years of initial treatment. In 2 % to 4 % of patients, relapse may occur later. The retroperitoneum is the primary site of late relapses, and alpha-fetoprotein is the predominant marker. These tumors are highly resistant to chemotherapy. Surgical resection is the preferred treatment. If the recurrent disease is inoperable, salvage chemotherapy may be instituted, followed by resection of the residual disease.

Original languageEnglish
Pages (from-to)518-524
Number of pages7
JournalCurrent Urology Reports
Issue number5
StatePublished - Oct 2013


  • Follow up
  • Germ cell tumor
  • Late relapse
  • Lymph node dissection
  • Malignant transformation
  • Recurrence
  • Retroperitoneum
  • Seminoma
  • Teratoma
  • Testis
  • Yolk sack tumor


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