Laser soldering of pig skin in vivo using IR fiber-optic temperature control system

D. Simhon, A. Ravid, M. Halpern, T. Brosh, T. Vasilyev, D. Levanon, N. Kariv, A. Katzir

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background and objectives: A feedback temperature controlled laser soldering system was used for bonding cut wounds on the skins of young and mature pigs. This is a step towards clinical implantation of this promising novel technique. Materials and methods: 47% bovine serum albumin (BSA) solder was applied onto cuts created in dorsally depilated skin on the backs of pigs, weighing 8 -10Kg or 74Kg. A temperature fiberoptic CO2 laser system was used to monitor and control the temperature of a spot on the cut at a desired temperature. For given values of time and temperature, a 28 days follow up of the soldered scars was obtained and compared with standard suturing. Results: Optimal soldering temperature was found to be 65°C. The tensile strength of laser-soldered cuts was measured after 3-28 days postoperatively and was found similar to that of sutured cuts. Macroscopic and microscopic studies showed better and faster wound healing of soldered scars compared with standard sutures. All soldered scars in the mature pig, demonstrated excellent healing with no signs of dehiscence. Conclusions: Temperature controlled laser soldering of cut wounds in pig skin offers several advantages over standard suturing techniques. This novel method should be tested clinically.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Issue number1
StatePublished - 14 Jun 2002


  • Albumin
  • CO laser
  • Fiberoptic
  • Histology
  • Infrared fibers
  • Laser soldering
  • Porcine model
  • Scar width
  • Suture
  • Temperature feedback control system
  • Tensile strength


Dive into the research topics of 'Laser soldering of pig skin in vivo using IR fiber-optic temperature control system'. Together they form a unique fingerprint.

Cite this