Laparoscopic versus open liver resection for metastatic colorectal cancer

I. Nachmany, N. Pencovich, N. Zohar, A. Ben-Yehuda, C. Binyamin, Y. Goykhman, N. Lubezky, R. Nakache, J. M. Klausner

Research output: Contribution to journalArticlepeer-review

Abstract

Background Application of minimally invasive surgery for oncologic liver resection is still limited to expert centers. We describe our experience in laparoscopic liver resection (LLR) for colorectal liver metastases (CLM). Patients and methods Between February 2010 and February 2015, 174 patients underwent resection of CLM. LLR was chosen according to surgeon's preferences. Data was retrieved from the institutes' electronic charts and retrospectively analyzed. Results LLR was performed in 42 patients (24.5%) and OLR in 132. Increased number of metastases were found in OLR (2.82 ± 2.81 versus 1.78 ± 1.16, P = 0.02), with no difference in maximal lesion size (33.1 ± 22 versus 34.9 ± 27.5 cm, P = 0.7). Altogether 55 patients underwent major hepatectomy, and 50 of the OLR group (37.8%, 37 right hepatectomy and 7 left hepatectomy) (P = 0.02). In 5 patients (11.6%) a conversion to open surgery was indicated. Operative time was longer in LLR. Estimated blood loss was decreased in laparoscopic minor resections. One OLR patient died during the postoperative period (0.7%). Eight patients in the OLR group had major complications, versus 1 in the LLR group (P = 0.0016). Reoperation within 30 days was performed in 4 OLR patients and none in the LLR group. Patients in the LLR group had shorter length of stay (LOS) (6.78 ± 2.75 versus 8.39 ± 5.64 days, P = 0.038). R0 resection was 88% in both groups. Conclusions In selected patients with CLM, LLR is feasible, safe and may achieve shorter LOS without inferior oncologic outcome.

Original languageEnglish
Pages (from-to)1615-1620
Number of pages6
JournalEuropean Journal of Surgical Oncology
Volume41
Issue number12
DOIs
StatePublished - 1 Dec 2015

Keywords

  • Hepatectomy
  • Laparoscopy
  • Liver resection
  • Metastasis
  • Surgery

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