Lack of effect of cannabinoids on carbonic anhydrase

Dalia Maor; Therese Treves; A. D. Korczyn

doi:10.1007/BF01245226

Lack of effect of cannabinoids on carbonic anhydrase

Dalia Maor^*, Therese Treves, A. D. Korczyn

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Cannabinoids have significant anticonvulsant effects, the mechanism of which is obscure. In addition, these agents reduce intraocular pressure. Inhibitors of carbonic anhydrase also share these two pharmacological actions. In order to investigate whether these actions of Cannabinoids are mediated through inhibition of carbonic anhydrase (CA), commercial solutions of the enzyme were exposed to Δ⁹-tetrahydrocannabinol and cannabidiol. No inhibition was observed at concentrations of 10^-7-10^-6 M.

Original language	English
Pages (from-to)	205-206
Number of pages	2
Journal	Journal of Neural Transmission
Volume	49
Issue number	3
DOIs	https://doi.org/10.1007/BF01245226
State	Published - Sep 1980

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/BF01245226

Cite this

@article{50a73c2ad84340cab69b0efce3bcbbe4,

title = "Lack of effect of cannabinoids on carbonic anhydrase",

abstract = "Cannabinoids have significant anticonvulsant effects, the mechanism of which is obscure. In addition, these agents reduce intraocular pressure. Inhibitors of carbonic anhydrase also share these two pharmacological actions. In order to investigate whether these actions of Cannabinoids are mediated through inhibition of carbonic anhydrase (CA), commercial solutions of the enzyme were exposed to Δ9-tetrahydrocannabinol and cannabidiol. No inhibition was observed at concentrations of 10-7-10-6 M.",

author = "Dalia Maor and Therese Treves and Korczyn, {A. D.}",

year = "1980",

month = sep,

doi = "10.1007/BF01245226",

language = "אנגלית",

volume = "49",

pages = "205--206",

journal = "Journal of Neural Transmission",

issn = "0300-9564",

publisher = "Springer",

number = "3",

}

TY - JOUR

T1 - Lack of effect of cannabinoids on carbonic anhydrase

AU - Maor, Dalia

AU - Treves, Therese

AU - Korczyn, A. D.

PY - 1980/9

Y1 - 1980/9

N2 - Cannabinoids have significant anticonvulsant effects, the mechanism of which is obscure. In addition, these agents reduce intraocular pressure. Inhibitors of carbonic anhydrase also share these two pharmacological actions. In order to investigate whether these actions of Cannabinoids are mediated through inhibition of carbonic anhydrase (CA), commercial solutions of the enzyme were exposed to Δ9-tetrahydrocannabinol and cannabidiol. No inhibition was observed at concentrations of 10-7-10-6 M.

AB - Cannabinoids have significant anticonvulsant effects, the mechanism of which is obscure. In addition, these agents reduce intraocular pressure. Inhibitors of carbonic anhydrase also share these two pharmacological actions. In order to investigate whether these actions of Cannabinoids are mediated through inhibition of carbonic anhydrase (CA), commercial solutions of the enzyme were exposed to Δ9-tetrahydrocannabinol and cannabidiol. No inhibition was observed at concentrations of 10-7-10-6 M.

UR - http://www.scopus.com/inward/record.url?scp=0019175489&partnerID=8YFLogxK

U2 - 10.1007/BF01245226

DO - 10.1007/BF01245226

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0019175489

SN - 0300-9564

VL - 49

SP - 205

EP - 206

JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

IS - 3

ER -

Lack of effect of cannabinoids on carbonic anhydrase

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this