TY - JOUR
T1 - Laboratory assessment and diagnosis of congenital viral infections
T2 - Rubella, cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV)
AU - Mendelson, Ella
AU - Aboudy, Yair
AU - Smetana, Zahava
AU - Tepperberg, Michal
AU - Grossman, Zahava
PY - 2006/5
Y1 - 2006/5
N2 - Viral infections during pregnancy may cause fetal or neonatal damage. Clinical intervention, which is required for certain viral infections, relies on laboratory tests performed during pregnancy and at the neonatal stage. This review describes traditional and advanced laboratory approaches and testing methods used for assessment of the six most significant viral infections during pregnancy: rubella virus (RV), cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV). Interpretation of the laboratory tests results according to studies published in recent years is discussed.
AB - Viral infections during pregnancy may cause fetal or neonatal damage. Clinical intervention, which is required for certain viral infections, relies on laboratory tests performed during pregnancy and at the neonatal stage. This review describes traditional and advanced laboratory approaches and testing methods used for assessment of the six most significant viral infections during pregnancy: rubella virus (RV), cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV), parvovirus B19 and human immunodeficiency virus (HIV). Interpretation of the laboratory tests results according to studies published in recent years is discussed.
KW - Congenital viral infections
KW - Cytomegalovirus (CMV)
KW - Herpes simplex virus (HSV)
KW - Human immunodeficiency virus (HIV)
KW - Laboratory diagnosis
KW - Parvovirus B19
KW - Rubella
KW - Varicella-zoster virus (VZV)
UR - http://www.scopus.com/inward/record.url?scp=33646473360&partnerID=8YFLogxK
U2 - 10.1016/j.reprotox.2006.02.001
DO - 10.1016/j.reprotox.2006.02.001
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C2 - 16564672
AN - SCOPUS:33646473360
SN - 0890-6238
VL - 21
SP - 350
EP - 382
JO - Reproductive Toxicology
JF - Reproductive Toxicology
IS - 4
ER -