The various mechanisms which can explain renal complications following the use of contrast dyes for pyelography are reviewed. Observation of the histological and pathophysiological changes, following injection of dyes, with considerations of the many predisposing factors, has permitted us to propose the possible pathways of renal toxicity. Pre existing renal vascular disease of any etiology is a very important factor. This has been confirmed by the observation of 4 cases of acute renal failure following high dose pyelography in diabetic patients with chronic renal disease. From this observation and a review of the extensive literature available, the authors show chemically the possible pathways of renal damage and what can be done to avoid this damage in a predisposed patient when a pyelography is essential.
|Translated title of the contribution||Renal toxicity of contrast dyes used for pyelography|
|Number of pages||7|
|State||Published - 1975|