TY - JOUR
T1 - L-deamino-8-d-Arginine Vasopressin Treatment in Pregnancy and Neonatal Outcome
T2 - A Report of Three Cases
AU - Linder, Nejama
AU - Matoth, Israel
AU - Ohel, Gonen
AU - Yourish, Debora
AU - Tamir, Israel
PY - 1986/7
Y1 - 1986/7
N2 - Three women with neurohypophyseal diabetes insipidus, treated for prolonged periods, including pregnancy, with L-deamino-8-d-arginine vasopressin, gave birth in our hospital. Two of the infants had severe congenital heart disease, one of which was associated with trisomy 21. The third baby, born prematurely, presented with mild intrauterine growth retardation; at the age of 21 months, the boy had severe failure to thrive, hypotonia, and motor retardation. These three cases raise doubts as to the safety of diabetes insipidus or its treatment in pregnancy.
AB - Three women with neurohypophyseal diabetes insipidus, treated for prolonged periods, including pregnancy, with L-deamino-8-d-arginine vasopressin, gave birth in our hospital. Two of the infants had severe congenital heart disease, one of which was associated with trisomy 21. The third baby, born prematurely, presented with mild intrauterine growth retardation; at the age of 21 months, the boy had severe failure to thrive, hypotonia, and motor retardation. These three cases raise doubts as to the safety of diabetes insipidus or its treatment in pregnancy.
UR - http://www.scopus.com/inward/record.url?scp=0022515430&partnerID=8YFLogxK
U2 - 10.1055/s-2007-999859
DO - 10.1055/s-2007-999859
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C2 - 3718635
AN - SCOPUS:0022515430
SN - 0735-1631
VL - 3
SP - 165
EP - 167
JO - American Journal of Perinatology
JF - American Journal of Perinatology
IS - 3
ER -
