Keratoconus and mitral valve prolapse

H. Lichter*, N. Loya, A. Sagie, N. Cohen, L. Muzmacher, Y. Yassur, D. Weinberger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

PURPOSE: To investigate the prevalence of keratoconus in patients with mitral valve prolapse (MVP). METHODS: Videokeratography was performed in 36 patients (72 eyes) with an echocardiographic diagnosis of MVP, and were compared with 25 controls. All participants underwent slit-lamp examination and completed a medical questionnaire about joint hypermobility, arthralgia, asthma, and allergic reactions. RESULTS: Keratoconus was found in eight eyes (11.1%) (P = .056) of eight patients (22.2%) (P = .049) in the MVP group and in one eye (2%) of one patient (4%) in the control group. The keratoconus was unilateral and asymptomatic in all cases. Conjunctival papillae were statistical significant higher in the MVP group (P = .015). A statistically significant intergroup difference existed in the presence of an allergic reaction (P = .001), but not in arthralgia, hypermobility of joints, or asthma. CONCLUSION: A borderline important association of MVP with keratoconus and with allergy exists. Patients with mitral valve prolapse complaining of poor vision should be suspected of having keratoconus. Copyright (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)667-668
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume129
Issue number5
DOIs
StatePublished - May 2000

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