Keloid-like scleroderma

Aviv Barzilai*, Anna Lyakhovitsky, Ada Horowitz, Henri Trau

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

A 62-year-old female who developed concomitantly acrosclerosis and keloid-like lesions is described. Biopsy specimens from these linear lesions showed a fibrous proliferation in the dermis composed mostly of normal-appearing, horizontally oriented collagen bundles and myofibroblasts, thus resembling a scar. Keloidal scleroderma is a rare variant of scleroderma. The diagnosis is considered for patients with scleroderma who develop lesions clinically and histologically indistinguishable from keloids. This case demonstrates for the first time that the histopathologic findings can mimic those of a scar, rather than a keloid, and hence is appropriately designated as keloid-like scleroderma. Clinical pathological correlation is mandatory for the correct diagnosis.

Original languageEnglish
Pages (from-to)327-330
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume25
Issue number4
DOIs
StatePublished - Aug 2003

Keywords

  • Fibrosis
  • Keloid
  • Morphea
  • Myofibroblast
  • Scleroderma

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