Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

Marie Wetterslev; Walter P. Maksymowych; Robert GW Lambert; Iris Eshed; Susanne J. Pedersen; Maria S. Stoenoiu; Simon Krabbe; Paul Bird; Violaine Foltz; Ashish J. Mathew; Frédérique Gandjbakhch; Joel Paschke; Philippe Carron; Gabriele De Marco; Helena Marzo-Ortega; Anna EF Poulsen; Jacob L. Jaremko; Philip G. Conaghan; Mikkel Østergaard

doi:10.1016/j.semarthrit.2021.05.013

Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

Marie Wetterslev^*
, Walter P. Maksymowych
, Robert GW Lambert
, Iris Eshed
, Susanne J. Pedersen
, Maria S. Stoenoiu
, Simon Krabbe
, Paul Bird
, Violaine Foltz
, Ashish J. Mathew
, Frédérique Gandjbakhch
, Joel Paschke
, Philippe Carron
, Gabriele De Marco
, Helena Marzo-Ortega
, Anna EF Poulsen
, Jacob L. Jaremko
, Philip G. Conaghan
, Mikkel Østergaard

^*Corresponding author for this work

Diagnostic Imaging

Center for Rheumatology and Spine Diseases
University of Copenhagen
University of Alberta
CARE Arthritis
MIC Medical Imaging
Université catholique de Louvain
University of New South Wales
Sorbonne Université
Ghent University
University of Leeds
Leeds Teaching Hospitals NHS Trust

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Objective: To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). Methods: Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. Results: In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion). Conclusion: MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.

Original language	English
Pages (from-to)	933-939
Number of pages	7
Journal	Seminars in Arthritis and Rheumatism
Volume	51
Issue number	4
DOIs	https://doi.org/10.1016/j.semarthrit.2021.05.013
State	Published - Aug 2021

Funding

Funders
CARE Arthritis Limited
National Institute for Health and Care Research
Leeds Biomedical Research Centre

Keywords

KIMRISS
Knee
MRI-WIPE
OMERACT
Spondyloarthritis
Whole-body MRI

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10.1016/j.semarthrit.2021.05.013

Cite this

Wetterslev, M., Maksymowych, W. P., Lambert, R. GW., Eshed, I., Pedersen, S. J., Stoenoiu, M. S., Krabbe, S., Bird, P., Foltz, V., Mathew, A. J., Gandjbakhch, F., Paschke, J., Carron, P., De Marco, G., Marzo-Ortega, H., Poulsen, A. EF., Jaremko, J. L., Conaghan, P. G., & Østergaard, M. (2021). Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores. Seminars in Arthritis and Rheumatism, 51(4), 933-939. https://doi.org/10.1016/j.semarthrit.2021.05.013

@article{cbd3ba31d9c44d76b9d4d30b42b135d5,

title = "Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores",

abstract = "Objective: To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). Methods: Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. Results: In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion). Conclusion: MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.",

keywords = "KIMRISS, Knee, MRI-WIPE, OMERACT, Spondyloarthritis, Whole-body MRI",

author = "Marie Wetterslev and Maksymowych, \{Walter P.\} and Lambert, \{Robert GW\} and Iris Eshed and Pedersen, \{Susanne J.\} and Stoenoiu, \{Maria S.\} and Simon Krabbe and Paul Bird and Violaine Foltz and Mathew, \{Ashish J.\} and Fr{\'e}d{\'e}rique Gandjbakhch and Joel Paschke and Philippe Carron and \{De Marco\}, Gabriele and Helena Marzo-Ortega and Poulsen, \{Anna EF\} and Jaremko, \{Jacob L.\} and Conaghan, \{Philip G.\} and Mikkel {\O}stergaard",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = aug,

doi = "10.1016/j.semarthrit.2021.05.013",

language = "אנגלית",

volume = "51",

pages = "933--939",

journal = "Seminars in Arthritis and Rheumatism",

issn = "0049-0172",

publisher = "W.B. Saunders",

number = "4",

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Wetterslev, M, Maksymowych, WP, Lambert, RGW, Eshed, I, Pedersen, SJ, Stoenoiu, MS, Krabbe, S, Bird, P, Foltz, V, Mathew, AJ, Gandjbakhch, F, Paschke, J, Carron, P, De Marco, G, Marzo-Ortega, H, Poulsen, AEF, Jaremko, JL, Conaghan, PG & Østergaard, M 2021, 'Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores', Seminars in Arthritis and Rheumatism, vol. 51, no. 4, pp. 933-939. https://doi.org/10.1016/j.semarthrit.2021.05.013

TY - JOUR

T1 - Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

AU - Wetterslev, Marie

AU - Maksymowych, Walter P.

AU - Lambert, Robert GW

AU - Eshed, Iris

AU - Pedersen, Susanne J.

AU - Stoenoiu, Maria S.

AU - Krabbe, Simon

AU - Bird, Paul

AU - Foltz, Violaine

AU - Mathew, Ashish J.

AU - Gandjbakhch, Frédérique

AU - Paschke, Joel

AU - Carron, Philippe

AU - De Marco, Gabriele

AU - Marzo-Ortega, Helena

AU - Poulsen, Anna EF

AU - Jaremko, Jacob L.

AU - Conaghan, Philip G.

AU - Østergaard, Mikkel

PY - 2021/8

Y1 - 2021/8

N2 - Objective: To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). Methods: Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. Results: In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion). Conclusion: MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.

AB - Objective: To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA). Methods: Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises. Results: In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion). Conclusion: MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.

KW - KIMRISS

KW - Knee

KW - MRI-WIPE

KW - OMERACT

KW - Spondyloarthritis

KW - Whole-body MRI

UR - https://www.scopus.com/pages/publications/85108731374

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DO - 10.1016/j.semarthrit.2021.05.013

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C2 - 34176643

AN - SCOPUS:85108731374

SN - 0049-0172

VL - 51

SP - 933

EP - 939

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

IS - 4

ER -

Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

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