TY - JOUR
T1 - IVF-ET in women with refractory polycystic ovarian disease
AU - Ashkenazi, Jack
AU - Feldberg, Dov
AU - Dicker, Dov
AU - Yeshaya, Arie
AU - Ayalon, Daniel
AU - Goldman, Jack A.
PY - 1989/2
Y1 - 1989/2
N2 - Polycystic ovarian disease may be a cause of hormonal infertility. This condition is often refractory to therapy. Three groups of randomly chosen women with refractory polycystic ovarian disease (PCOD) were treated by induction of ovulation with pFSH/hCG, pFSH/hMG/hCG or after down-regulation of the ovaries with a GnRH analogue (Decapeptyl). Out of 18 patients six conceived in the first in vitro fertilization-embryo transfer (IVF-ET) cycle, and two further women conceived in a later cycle. It is suggested that patients with refractory PCOD should be referred for IVF-ET therapy, possibly after treatment with a GnRH analogue.
AB - Polycystic ovarian disease may be a cause of hormonal infertility. This condition is often refractory to therapy. Three groups of randomly chosen women with refractory polycystic ovarian disease (PCOD) were treated by induction of ovulation with pFSH/hCG, pFSH/hMG/hCG or after down-regulation of the ovaries with a GnRH analogue (Decapeptyl). Out of 18 patients six conceived in the first in vitro fertilization-embryo transfer (IVF-ET) cycle, and two further women conceived in a later cycle. It is suggested that patients with refractory PCOD should be referred for IVF-ET therapy, possibly after treatment with a GnRH analogue.
KW - GnRH analogue
KW - In vitro fertilization
KW - Polycystic ovarian disease
UR - http://www.scopus.com/inward/record.url?scp=0024497060&partnerID=8YFLogxK
U2 - 10.1016/0028-2243(89)90063-4
DO - 10.1016/0028-2243(89)90063-4
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AN - SCOPUS:0024497060
SN - 0028-2243
VL - 30
SP - 157
EP - 161
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
IS - 2
ER -