Is cord blood erythropoietin a marker of intrapartum hypoxia?

A. Halevi, S. Dollberg, D. Manor, R. Nussinovich, R. Kaempfer, R. Gale

Research output: Contribution to journalArticlepeer-review


A sensitive assay was used to compare the biological activity of cord serum erythropoietin in two groups of infants born with or without labor-induced hypoxia. The mean cord serum erythropoietin activity in 161 infants delivered after vaginal labor was 116 +/- 36 mU/mL, and was indistinguishable from that observed in 23 infants delivered by preplanned, elective cesarean section, 114 +/- 12 mU/mL (P = .75). The bioassay measured effective erythropoietin activity, including the contribution of potentiators in serum. These results indicate that duration and intensity of labor are insufficient to cause a significant increase in effective erythropoietin activity.

Original languageEnglish
Pages (from-to)215-219
Number of pages5
JournalJournal of Perinatology
Issue number3
StatePublished - Sep 1992
Externally publishedYes


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