Is cancer an autoimmune process dependent on anti-apoptotic autoantibodies?

Y. Bar-Dayan*, S. V. Kaveri, M. D. Kazatchkine, Y. Shoenfeld

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Dysregulated apoptosis is a potentially important mechanism in the pathogenesis of cancer. Autoantibodies, which inhibit apoptosis, have recently been identified in patients with malignant diseases. We suggest that such inhibitory autoantibodies participate in tumorigenesis. These views may provide a basis for the increased incidence of cancer in patients with autoimmune diseases and have novel therapeutic implications for cancer. (C) 2000 Harcourt Publishers Ltd.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalMedical Hypotheses
Issue number2
StatePublished - Aug 2000
Externally publishedYes


Dive into the research topics of 'Is cancer an autoimmune process dependent on anti-apoptotic autoantibodies?'. Together they form a unique fingerprint.

Cite this