Abstract
Dysregulated apoptosis is a potentially important mechanism in the pathogenesis of cancer. Autoantibodies, which inhibit apoptosis, have recently been identified in patients with malignant diseases. We suggest that such inhibitory autoantibodies participate in tumorigenesis. These views may provide a basis for the increased incidence of cancer in patients with autoimmune diseases and have novel therapeutic implications for cancer. (C) 2000 Harcourt Publishers Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 103-108 |
| Number of pages | 6 |
| Journal | Medical Hypotheses |
| Volume | 55 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 2000 |
| Externally published | Yes |
