Cylindrical optical fibers, made of various materials, have been used for decades for chemical and biological sensing. Optical fibers transparent in the mid-infrared (IR) enable absorption measurements in remote locations. New techniques will enable the use of IR fibers for measurements in ATR-mode. If the fiber is in contact with a sample that has characteristic absorption lines, the total transmission of the fiber and sample of these lines will decrease. In this way the absorption of a sample can be determined using a non-destructive method. This work proves that flattened silver halide fibers could be useful as sensing elements in analytical systems. First measurements using flattened IR-fibers have been carried out on biological targets. The experimental set-up used was made up of an FTIR-spectrometer, fiber optic cables and an external detector. A segment of 1.9 cm at the center of the fiber was flattened to approximately 100-150 μm. Transmission spectra of flattened fibers have been compared to those of the cylindrical fibers. IR-spectra were recorded for biochemical compounds such as glucose, bovine serum albumin (BSA), gelatin and bio-fluids, and native tissue was compared to coagulated tissue. Spectral differences were obtained indicating a possible use for the study of thermal damage in tissues.
|Number of pages||10|
|Journal||Sensors and Actuators, B: Chemical|
|State||Published - 15 Apr 2001|
|Event||5th European Conference on Optical Chemical Sensors and Biosensors - Lyon, France|
Duration: 16 Apr 2000 → 19 Apr 2000
- Fiber evanescent wave spectroscopy (FEWS)
- Flattened IR-fiber