TY - JOUR
T1 - Intravenous immunoglobulin for immunomodulation of systemic lupus erythematosus
AU - Sherer, Yaniv
AU - Shoenfeld, Yehuda
PY - 2006/2
Y1 - 2006/2
N2 - Intravenous immunoglobulin (IVIg) is used for replacement therapy in immunodeficiency states and for immunomodulation of various autoimmune diseases. Several case reports and series support a beneficial role of IVIg in systemic lupus erythematosus (SLE), both as salvage immunotherapy and in control of disease activity in general and amelioration of classical disease manifestations. Further, lupus nephritis can also be treated usually successfully with IVIg. A few questions remain unanswered as to the appropriate therapeutic dosage and the clinical manifestations that can be best treated with IVIg.
AB - Intravenous immunoglobulin (IVIg) is used for replacement therapy in immunodeficiency states and for immunomodulation of various autoimmune diseases. Several case reports and series support a beneficial role of IVIg in systemic lupus erythematosus (SLE), both as salvage immunotherapy and in control of disease activity in general and amelioration of classical disease manifestations. Further, lupus nephritis can also be treated usually successfully with IVIg. A few questions remain unanswered as to the appropriate therapeutic dosage and the clinical manifestations that can be best treated with IVIg.
KW - Immunomodulation
KW - Intravenous immunoglobulin
KW - Systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=31144472862&partnerID=8YFLogxK
U2 - 10.1016/j.autrev.2005.09.002
DO - 10.1016/j.autrev.2005.09.002
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AN - SCOPUS:31144472862
SN - 1568-9972
VL - 5
SP - 153
EP - 155
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 2 SPEC. ISS.
ER -