Intracytoplasmic inclusions in the peripheral blood lymphocytes of patients with chronic lymphatic leukemia

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Abstract

An ultrastructural survey of peripheral blood lymphocytes in 81 patients with chronic lymphatic leukemia (CLL) demonstrated intracytoplasmic inclusions in 15 of them. These inclusions consisted of round, dense bodies, ferritin deposits, lipid-containing bodies, concentric rings of endoplasmic reticulum, microfibrillar formations and crystalloid inclusions. The variety of these inclusions suggests that cases diagnosed by light microscopy as classical CLL are actually subtypes which may differ in their clinical course and ultimate prognosis.

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalVirchows Archiv B Cell Pathology Including Molecular Pathology
Volume42
Issue number1
DOIs
StatePublished - Dec 1983

Keywords

  • Chronic lymphatic leukemia
  • Intracytoplasmic inclusions
  • Lymphocytes
  • Ultrastructure

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