TY - JOUR
T1 - Intracranial Hemorrhage in the Preterm Infant
T2 - Understanding It, Preventing It
AU - Bassan, Haim
N1 - Funding Information:
Haim Bassan is supported by the Tel Aviv Sourasky Medical Center Research Fund.
PY - 2009/12
Y1 - 2009/12
N2 - New discoveries in neonatal imaging, cerebral monitoring, and hemodynamics, and greater understanding of inflammatory and genetic mechanisms involved in intracranial hemorrhage (ICH) in the preterm infant are creating opportunities for innovative early detection and prevention approaches. This article covers the spectrum of ICH in the preterm infant, including germinal matrix intraventricular hemorrhage, its complications, and associated phenomena, such as the emerging role of cerebellar hemorrhage. The overall aim of this article is to review the current knowledge of the mechanisms, diagnosis, outcome, and management of preterm ICH; to revisit the origins from which they develop; and to discuss future expectations.
AB - New discoveries in neonatal imaging, cerebral monitoring, and hemodynamics, and greater understanding of inflammatory and genetic mechanisms involved in intracranial hemorrhage (ICH) in the preterm infant are creating opportunities for innovative early detection and prevention approaches. This article covers the spectrum of ICH in the preterm infant, including germinal matrix intraventricular hemorrhage, its complications, and associated phenomena, such as the emerging role of cerebellar hemorrhage. The overall aim of this article is to review the current knowledge of the mechanisms, diagnosis, outcome, and management of preterm ICH; to revisit the origins from which they develop; and to discuss future expectations.
KW - Cerebellar hemorrhage
KW - Genetic
KW - Germinal matrix
KW - Intraventricular hemorrhage
KW - Periventricular hemorrhagic infarction
KW - Posthemorrhagic hydrocephalus
KW - Prematurity
KW - Terminal vein
UR - http://www.scopus.com/inward/record.url?scp=70450285603&partnerID=8YFLogxK
U2 - 10.1016/j.clp.2009.07.014
DO - 10.1016/j.clp.2009.07.014
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C2 - 19944833
AN - SCOPUS:70450285603
SN - 0095-5108
VL - 36
SP - 737
EP - 762
JO - Clinics in Perinatology
JF - Clinics in Perinatology
IS - 4
ER -
