Abstract
We evaluated data from 1,205 patients treated with intravenous recombinant tissue plasminogen activator (rt-PA) for acute ischemic stroke within 3 hours of symptom onset to identify pretreatment predictors of rt-PA-related intracerebral hemorrhage. Our findings suggest stroke severity, diabetes mellitus, increasing serum glucose, early ischemic changes on computed tomography, and decreasing platelet counts are associated with thrombolysis-related intracerebral hemorrhage. These risk factors may help physicians identify patients at high and low risk for rt-PA treatment and better understand the pathophysiology of thrombosis-related intracerebral hemorrhage.
Original language | English |
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Pages (from-to) | 17-20 |
Number of pages | 4 |
Journal | Cardiology Review |
Volume | 19 |
Issue number | 12 |
State | Published - Oct 2002 |
Externally published | Yes |