Intracardiac echogenic focus: No apparent association with structural cardiac abnormality

Igal Wolman*, Ariel Jaffa, Eli Geva, Shmuel Diamant, Simon Strauss, Joseph B. Lessing, Yuval Yaron

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objective: The aim of our study was to evaluate whether intracardiac echogenic foci (ICEFs) may be associated with increased risk for structural cardiac anomalies in the low-risk population. Methods: During a 24-month period, 3,744 low-risk patients were prospectively screened for ICEFs by prenatal sonography. The study group was composed of 138 fetuses (3.7%) with ICEF. The control group was composed of 167 fetuses without ICEF. In all fetuses a complete echocardiographic evaluation was performed. Results: Among the 138 fetuses in the study group, 108 (78%) ICEFs were found in the left ventricle, 25 (18%) were found in the right ventricle, and 5 (4%) were found to be bilateral. No statistically significant difference was found between the study and the control group regarding the presence of cardiac anomalies. Only 1 case (0.7%) of pulmonic stenosis was found in the study group, compared to 1 case (0.6%) of bicuspid aortic valve in the control group. Conclusions: We conclude that ICEFs found in low-risk patients are not associated with a significant increase in the risk of cardiac anomalies. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish
Pages (from-to)216-218
Number of pages3
JournalFetal Diagnosis and Therapy
Issue number4
StatePublished - 2000


  • Cardiac abnormalities
  • Intracardiac echogenic focus
  • Ultrasound screening


Dive into the research topics of 'Intracardiac echogenic focus: No apparent association with structural cardiac abnormality'. Together they form a unique fingerprint.

Cite this