Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation

Florence Lacaille; Girish Gupte; Virginie Colomb; Lorenzo D'antiga; Corina Hartman; Iva Hojsak; Sanja Kolacek; John Puntis; Raanan Shamir

doi:10.1097/MPG.0000000000000586

Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation

Florence Lacaille, Girish Gupte^*, Virginie Colomb, Lorenzo D'antiga, Corina Hartman, Iva Hojsak, Sanja Kolacek, John Puntis, Raanan Shamir

^*Corresponding author for this work

Pediatrics

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184 Scopus citations

Abstract

Intestinal failure-associated liver disease is the most prevalent complication affecting children with intestinal failure receiving long-term parenteral nutrition. This paper reviews the definition, diagnostic criteria, pathogenesis, and risk factors. The authors discuss the role of enteral nutrition, parenteral nutrition, and its components, especially lipid emulsions. The authors also discuss the surgical treatment, including intestinal transplantation, its indications, technique, and results, and emphasise the importance of specialised intestinal failure centres.

Original language	English
Pages (from-to)	272-283
Number of pages	12
Journal	Journal of Pediatric Gastroenterology and Nutrition
Volume	60
Issue number	2
DOIs	https://doi.org/10.1097/MPG.0000000000000586
State	Published - 6 Feb 2015

Keywords

intestinal failure
intestinal failure-associated liver disease
lipids
parenteral nutrition
parenteral nutrition-associated liver disease
portal hypertension
small bowel transplantation

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10.1097/MPG.0000000000000586

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Lacaille, F., Gupte, G., Colomb, V., D'antiga, L., Hartman, C., Hojsak, I., Kolacek, S., Puntis, J., & Shamir, R. (2015). Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation. Journal of Pediatric Gastroenterology and Nutrition, 60(2), 272-283. https://doi.org/10.1097/MPG.0000000000000586

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title = "Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation",

abstract = "Intestinal failure-associated liver disease is the most prevalent complication affecting children with intestinal failure receiving long-term parenteral nutrition. This paper reviews the definition, diagnostic criteria, pathogenesis, and risk factors. The authors discuss the role of enteral nutrition, parenteral nutrition, and its components, especially lipid emulsions. The authors also discuss the surgical treatment, including intestinal transplantation, its indications, technique, and results, and emphasise the importance of specialised intestinal failure centres.",

keywords = "intestinal failure, intestinal failure-associated liver disease, lipids, parenteral nutrition, parenteral nutrition-associated liver disease, portal hypertension, small bowel transplantation",

author = "Florence Lacaille and Girish Gupte and Virginie Colomb and Lorenzo D'antiga and Corina Hartman and Iva Hojsak and Sanja Kolacek and John Puntis and Raanan Shamir",

note = "Publisher Copyright: {\textcopyright} 2015 by ESPGHAN and NASPGHAN.",

year = "2015",

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doi = "10.1097/MPG.0000000000000586",

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Lacaille, F, Gupte, G, Colomb, V, D'antiga, L, Hartman, C, Hojsak, I, Kolacek, S, Puntis, J & Shamir, R 2015, 'Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation', Journal of Pediatric Gastroenterology and Nutrition, vol. 60, no. 2, pp. 272-283. https://doi.org/10.1097/MPG.0000000000000586

Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation. / Lacaille, Florence; Gupte, Girish; Colomb, Virginie et al.
In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 60, No. 2, 06.02.2015, p. 272-283.

Research output: Contribution to journal › Article › peer-review

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AU - Gupte, Girish

AU - Colomb, Virginie

AU - D'antiga, Lorenzo

AU - Hartman, Corina

AU - Hojsak, Iva

AU - Kolacek, Sanja

AU - Puntis, John

AU - Shamir, Raanan

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KW - lipids

KW - parenteral nutrition

KW - parenteral nutrition-associated liver disease

KW - portal hypertension

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Intestinal failure-associated liver disease: A position paper of the ESPGHAN working group of intestinal failure and intestinal transplantation

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