TY - JOUR
T1 - Interventional Pharmacoeconomics
T2 - A Novel Mechanism for Unlocking Value
AU - Serritella, Anthony V.
AU - Strohbehn, Garth W.
AU - Goldstein, Daniel A.
AU - Lichter, Allen S.
AU - Ratain, Mark J.
N1 - Publisher Copyright:
© 2020 The Authors Clinical Pharmacology & Therapeutics © 2020 American Society for Clinical Pharmacology and Therapeutics
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Cancer care’s sustainability is challenged by drug expenditures. In the absence of systemic change, innovation is needed to curtail drug costs. Interventional pharmacoeconomics (IVPE) utilizes clinical research to identify safe, efficacious, cost-conscious dosing regimens to extract maximum value from expensive therapies. Strategies include de-escalation of dosage, treatment duration and administration frequency, and substitution with therapeutic alternatives. In this review, we discuss how IVPE strategies have been successfully used and could be implemented going forward.
AB - Cancer care’s sustainability is challenged by drug expenditures. In the absence of systemic change, innovation is needed to curtail drug costs. Interventional pharmacoeconomics (IVPE) utilizes clinical research to identify safe, efficacious, cost-conscious dosing regimens to extract maximum value from expensive therapies. Strategies include de-escalation of dosage, treatment duration and administration frequency, and substitution with therapeutic alternatives. In this review, we discuss how IVPE strategies have been successfully used and could be implemented going forward.
UR - http://www.scopus.com/inward/record.url?scp=85084511401&partnerID=8YFLogxK
U2 - 10.1002/cpt.1853
DO - 10.1002/cpt.1853
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C2 - 32298471
AN - SCOPUS:85084511401
SN - 0009-9236
VL - 108
SP - 487
EP - 493
JO - Clinical Pharmacology and Therapeutics
JF - Clinical Pharmacology and Therapeutics
IS - 3
ER -
