Intervention with the screening tool of older persons potentially inappropriate prescriptions/screening tool to alert doctors to right treatment criteria in elderly residents of a chronic geriatric facility: A randomized clinical trial

Objectives To assess the effect of a Screening Tool of Older Persons potentially inappropriate Prescriptions/Screening Tool to Alert doctors to Right Treatment (STOPP/START) medication intervention on clinical and economic outcomes. Design Parallel-group randomized trial. Setting Chronic care geriatric facility. Participants Residents aged 65 and older prescribed with at least one medication (N = 359) were randomized to receive usual pharmaceutical care or undergo medication intervention. Intervention Screening medications with STOPP/START criteria followed up with recommendations to the chief physician. Measurements The outcome measures assessed at the initiation of the intervention and 1 year later were number of hospitalizations and falls, Functional Independence Measure (FIM), quality of life (measured using the Medical Outcomes Study 12-item Short-Form Health Survey), and costs of medications. Results The average number of drugs prescribed was significantly lower in the intervention than in the control group after 1 year (P <.001). The average drug costs in the intervention group decreased by 103 shekels (US$29) per participant per month (P <.001). The average number of falls in the intervention group dropped significantly (P =.006). Rates of hospitalization, FIM scores, and quality of life measurements were similar for both groups. Conclusion Implementation of STOPP/START criteria reduced the number of medications, falls, and costs in a geriatric facility. Their incorporation in those and similar settings is recommended.