TY - JOUR
T1 - Interval training and the GH-IGF-I axis - A new look into an old training regimen
AU - Eliakim, Alon
AU - Nemet, Dan
PY - 2012/10/1
Y1 - 2012/10/1
N2 - Interval training is a commonly used training method known to improve both aerobic and anaerobic capabilities, and is one of the popular techniques used in training young athletes engaged in both anaerobic- and aerobic-type sports. This occurs although anaerobic glycolytic capacity is less efficient in the child and becomes increasingly more effective with age. The endocrine system, by modulation of anabolic and catabolic processes, plays a major role in the physiological adaptation to exercise training. In recent years, changes in circulating components of the growth hormone-insulin-like growth factor-1 axis, a system of growth mediators that control somatic and tissue growth, have been used to quantify the effects of training. Interestingly, exercise is also associated with remarkable changes in inflammatory cytokines, and the exercise-related response of these markers can also be used to gauge exercise load. The balance between these two seemingly antagonistic systems is believed to determine the effects of exercise. This review will summarize current knowledge on the balance of anabolic hormones and inflammatory mediators following anaerobic, interval exercise and training and its implication to young athletes.
AB - Interval training is a commonly used training method known to improve both aerobic and anaerobic capabilities, and is one of the popular techniques used in training young athletes engaged in both anaerobic- and aerobic-type sports. This occurs although anaerobic glycolytic capacity is less efficient in the child and becomes increasingly more effective with age. The endocrine system, by modulation of anabolic and catabolic processes, plays a major role in the physiological adaptation to exercise training. In recent years, changes in circulating components of the growth hormone-insulin-like growth factor-1 axis, a system of growth mediators that control somatic and tissue growth, have been used to quantify the effects of training. Interestingly, exercise is also associated with remarkable changes in inflammatory cytokines, and the exercise-related response of these markers can also be used to gauge exercise load. The balance between these two seemingly antagonistic systems is believed to determine the effects of exercise. This review will summarize current knowledge on the balance of anabolic hormones and inflammatory mediators following anaerobic, interval exercise and training and its implication to young athletes.
KW - Anabolic
KW - Exercise
KW - Growth hormone
KW - Interval training
UR - http://www.scopus.com/inward/record.url?scp=84867834955&partnerID=8YFLogxK
U2 - 10.1515/jpem-2012-0209
DO - 10.1515/jpem-2012-0209
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C2 - 23426806
AN - SCOPUS:84867834955
SN - 0334-018X
VL - 25
SP - 815
EP - 821
JO - Journal of Pediatric Endocrinology and Metabolism
JF - Journal of Pediatric Endocrinology and Metabolism
IS - 9-10
ER -