Interstitial pregnancy management and subsequent pregnancy outcome

Ron Sagiv, Abraham Debby, Ran Keidar, Ram Kerner, Abraham Golan

Research output: Contribution to journalArticlepeer-review


We report on management and subsequent fertility outcome of interstitial pregnancy in a retrospective cohort study (Canadian Task Force classification II-3) at a university affiliated teaching hospital. Of 706 women with extrauterine pregnancy, 14 consecutive women with interstitial pregnancy were treated by methotrexate, laparotomy or laparoscopy between 1997 and 2007. The first four women, with significant hemoperitoneum, were treated by laparotomy. Of the next 10 women, four were selected for medical treatment with methotrexate. Only one case was treated successfully. The other six women had laparoscopic treatment. Of nine laparoscopies, one was converted to laparotomy due to excessive blood loss during the procedure. Of nine women desiring a child, three were infertile, whereas six conceived with an intrauterine pregnancy. A change from diagnosis later in pregnancy and laparotomy to more conservative treatment, mainly by laparoscopy, suggests a possibly better subsequent pregnancy rate.

Original languageEnglish
Pages (from-to)1327-1330
Number of pages4
JournalActa Obstetricia et Gynecologica Scandinavica
Issue number11
StatePublished - Nov 2013


  • Ectopic pregnancy
  • interstitial pregnancy
  • laparoscopic surgery
  • medical treatment
  • methotrexate


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