TY - JOUR
T1 - Interstitial pneumonitis after total body irradiation
T2 - effect of partial lung shielding
AU - Weshler, Z.
AU - Breuer, R.
AU - Or, R.
AU - Naparstek, E.
AU - Pfeffer, M. R.
AU - Lowental, E.
AU - Slavin, S.
PY - 1990/1
Y1 - 1990/1
N2 - The potential beneficial effects of partial lung shielding were investigated in 44 patients conditioned by whole body radiotherapy as part of the conditioning for bone marrow transplantation (BMT). The first 23 patients were irradiated with fractionated total body irradiation (TBI) to a total dose of 12 Gy. In the second series of 21 patients a 50% transmission lung shield was utilized following 6 Gy TBI. This treatment was combined in the second group with four fractions of 1.5 Gy total lymphoid irradiation (TLI), given in 2 d. The rate of idiopathic interstitial pneumonitis (IP) was 26% in the first group, compared to none in the second.
AB - The potential beneficial effects of partial lung shielding were investigated in 44 patients conditioned by whole body radiotherapy as part of the conditioning for bone marrow transplantation (BMT). The first 23 patients were irradiated with fractionated total body irradiation (TBI) to a total dose of 12 Gy. In the second series of 21 patients a 50% transmission lung shield was utilized following 6 Gy TBI. This treatment was combined in the second group with four fractions of 1.5 Gy total lymphoid irradiation (TLI), given in 2 d. The rate of idiopathic interstitial pneumonitis (IP) was 26% in the first group, compared to none in the second.
UR - http://www.scopus.com/inward/record.url?scp=0025073327&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2141.1990.tb02538.x
DO - 10.1111/j.1365-2141.1990.tb02538.x
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C2 - 2178673
AN - SCOPUS:0025073327
VL - 74
SP - 61
EP - 64
JO - British Journal of Haematology
JF - British Journal of Haematology
SN - 0007-1048
IS - 1
ER -