Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix

D. Gilat*, L. Cahalon, R. Hershkoviz, O. Lider

*Corresponding author for this work

Research output: Contribution to journalComment/debate

Abstract

Following immunological insult, T cells migrate from blood vessels to inflammatory sites through the extracellular matrix (ECM). This movement is regulated by signals provided by proinflammatory mediators, including cytokines, chemokines and ECM-degrading enzymes. Here, Dalia Gilat and colleagues discuss the interactions between tissue-invading T cells and locally secreted, diffusible or ECM-anchored mediators.

Original languageEnglish
Pages (from-to)16-20
Number of pages5
JournalImmunology Today
Volume17
Issue number1
DOIs
StatePublished - 1996
Externally publishedYes

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