Interleukin-2 production and response to exogenous interleukin-2 in a patient with the acquired immune deficiency syndrome (AIDS)

G. J. Hauser, T. Bino, H. Rosenberg, V. Zakuth, E. Geller, Z. Spirer

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

The ability of lymphocytes from a patient suffering from the acquired immune deficiency syndrome (AIDS) to produce interleukin-2 (IL-2) was found to be comparable to that of his healthy sex partner and to that of a normal control. Addition of exogenous IL-2 to lymphocyte cultures did not improve the poor mitogen response to phytohaemagglutinin in this patient. Our data suggest that the underlying defect in this AIDS patient is due to an IL-2 receptor defect.

Original languageEnglish
Pages (from-to)14-17
Number of pages4
JournalClinical and Experimental Immunology
Volume56
Issue number1
StatePublished - 1984

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