Interferon-β-related DNA on human chromosome 4

Anurag D. Sagar, Pravinkumar B. Sehgal*, Lester T. May, Doris L. Slate, Lester Shulman, Peter E. Barker, Frank H. Ruddle

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A DNA subclone (pPE-4000) derived from the λB4 interferon-β-related human genomic DNA clone was used as a probe in blot-hybridization experiments of DNA from a panel of human-rodent somatic cell hybrids containing overlapping subsets of human chromosomes. The DNA hybridization experiments showed that the λB4 IFN-β locus is localized to human chromosome 4. A provisional regional assignment to 4q12-qter was also obtained. Thus available hybridization data implicate human chromosomes 2, 4, and 9 in the human IFN-β system while the available biological data also implicated human chromosome 5.

Original languageEnglish
Pages (from-to)403-408
Number of pages6
JournalSomatic Cell and Molecular Genetics
Issue number4
StatePublished - Jul 1985
Externally publishedYes


Dive into the research topics of 'Interferon-β-related DNA on human chromosome 4'. Together they form a unique fingerprint.

Cite this