TY - JOUR
T1 - Interference between Streptococcus pneumoniae and Staphylococcus aureus
T2 - In vitro hydrogen peroxide-mediated killing by Streptococcus pneumoniae
AU - Regev-Yochay, Gili
AU - Trzciński, Krzysztof
AU - Thompson, Claudette M.
AU - Malley, Richard
AU - Lipsitch, Marc
PY - 2006/7
Y1 - 2006/7
N2 - The bactericidal activity of Streptococcus pneumoniae toward Staphylococcus aureus is mediated by hydrogen peroxide. Catalase eliminated this activity. Pneumococci grown anaerobically or genetically lacking pyruvate oxidase (SpxB) were not bactericidal, nor were eonpneumococcal sirepiococci. These results provide a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies.
AB - The bactericidal activity of Streptococcus pneumoniae toward Staphylococcus aureus is mediated by hydrogen peroxide. Catalase eliminated this activity. Pneumococci grown anaerobically or genetically lacking pyruvate oxidase (SpxB) were not bactericidal, nor were eonpneumococcal sirepiococci. These results provide a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies.
UR - http://www.scopus.com/inward/record.url?scp=33745460121&partnerID=8YFLogxK
U2 - 10.1128/JB.00317-06
DO - 10.1128/JB.00317-06
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C2 - 16788209
AN - SCOPUS:33745460121
SN - 0021-9193
VL - 188
SP - 4996
EP - 5001
JO - Journal of Bacteriology
JF - Journal of Bacteriology
IS - 13
ER -