Interaction between Entamoeba histolytica and the immune system. I. Mitogenicity of Entamoeba histolytica extracts for human peripheral T lymphocytes

T. Diamanstein, M. Klos, D. Gold, H. Hahn

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of Entamoeba histolytica extracts (E.h.e.) on proliferation in vitro of human peripheral blood lympocytes, cord blood lymphocytes, and lymphocytes enriched for T cells or non-T cells was investigated. As tested by 3H-thymidine uptake and by morphologic criteria, E.h.e. stimulate T lymphocyte proliferation. Non-T lymphocytes do not respond to E.h.e. The response of lymphocytes to E.h.e. differed from their response to Con A in several respects, indicating either that E.h.e. and Con A act on different subsets of T cells or that E.h.e. act by different mechanism on the Con A reactive cells.

Original languageEnglish
Pages (from-to)2084-2086
Number of pages3
JournalJournal of Immunology
Volume126
Issue number6
StatePublished - 1981
Externally publishedYes

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