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Integrative oncology in clinical practice, research, and education: Middle-Eastern and global perspectives

  • Eran Ben-Arye*
  • , Tido von Schoen-Angerer
  • , Maryam Rassouli
  • , Gülbeyaz Can
  • , Mohamed Hablas
  • , Suha Omran
  • , Konstantina Stylianou
  • , Malak Rita Hajji
  • , Neil Arun Nijhawan
  • , Ibtisam Ghrayeb
  • , Nahla Gafer
  • , Georg Seifert
  • , Jianping Liu
  • , Alain Toledano
  • , Massimo Bonucci
  • , Ricardo Ghelman
  • , Nina Fuller-Shavel
  • , Rammanohar Puthiyedath
  • , Noah Samuels
  • , Lorenzo Cohen
  • *Corresponding author for this work
  • Technion-Israel Institute of Technology
  • Middle East Research Group in Integrative Oncology (MERGIO)
  • Carmel and Lin Medical Center
  • Society for Integrative Oncology (SIO) Regional Ambassador to Europe and the Middle East
  • International Federation of Anthroposophic Medical Associations IVAA
  • University of Geneva
  • Shahid Beheshti University of Medical Sciences
  • University of Nizwa
  • Istanbul University - Cerrahpaşa
  • Gharbia Cancer Society, Tanta
  • Jordan University of Science and Technology
  • German Oncology Center
  • ONCORAD Healthcare Group
  • Burjeel Medical City
  • Gulf Medical University
  • Makassed Hospital
  • Khartoum Oncology Hospital
  • Berlin Institute of Health
  • Beijing University of Chinese Medicine
  • Integrative Medicine Center
  • Hartmann Radiotherapy Institute
  • Conservatoire national des arts et métiers
  • Sapienza University of Rome
  • Humanitas University Consortium
  • ARTOI Foundation
  • CABSIN
  • Universidade Federal do Rio de Janeiro
  • British Society for Integrative Oncology (BSIO)
  • National Centre for Integrative Oncology (NCIO)
  • Integrative Cancer Care
  • Amrita Vishwa Vidyapeetham
  • Hebrew University of Jerusalem
  • University of Texas MD Anderson Cancer Center

Research output: Contribution to journalReview articlepeer-review

Abstract

This study aimed to explore integrative oncology (IO) across the Middle East, examine how international IO leaders promote IO in the Middle East, and assess how the Middle East contributes to the development of IO globally. This narrative review employed a structured literature search and descriptive analytic approach, using multiple databases, predefined keywords, varied study designs, and multilingual sources. It was conducted by a multi-disciplinary team of clinicians, researchers, and medical educators from ten Middle Eastern countries (Cyprus, Egypt, Iran, Israel, Jordan, Morocco, Palestine, Sudan, Turkey, and United Arab Emirates) and global IO/palliative leaders from South America, India, China, Europe, and the USA, providing a real-life implementation perspective. The collaborative IO model of care ensures safe and effective traditional and herbal medicine practices, with a culturally-sensitive approach respecting health beliefs. Middle Eastern and international IO participants discuss how they can benefit from each other, drawing from Middle-East Research Group in Integrative Oncology (MERGIO) activities in clinical practice, research, and medical education. Important themes derived from the review include the potential for IO to advance patient-centered care, effectively improve quality of life-related concerns, ensure a safe therapeutic environment, and overcome accessibility- and disparity-related barriers. IO treatments should be provided by trained multi-disciplinary teams of integrative physicians and practitioners, within culturally-adapted multi-modal programs and a receptive national and regional healthcare policy. Research utilizing pragmatic methodologies reflects real-world IO practice, with IO prioritized in medical education providing students and healthcare professionals with high-quality clinical and research training across the Middle East.

Original languageEnglish
Article number453
JournalSupportive Care in Cancer
Volume34
Issue number5
DOIs
StatePublished - May 2026
Externally publishedYes

Funding

Funders
Technion-Israel Institute of Technology

    Keywords

    • Integrative oncology
    • Middle-East
    • Palliative care
    • Supportive cancer care
    • Traditional Arab Islamic medicine
    • Traditional medicine

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