Initial clinical testing of a multi-spectral imaging system built on a smartphone platform

Jonah W. Mink, Shraga Wexler, Frank J. Bolton, Charles Hummel, Bruce S. Kahn, David Levitz*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Multi-spectral imaging systems are often expensive and bulky. An innovative multi-spectral imaging system was fitted onto a mobile colposcope, an imaging system built around a smartphone in order to image the uterine cervix from outside the body. The multi-spectral mobile colposcope (MSMC) acquires images at different wavelengths. This paper presents the clinical testing of MSMC imaging (technical validation of the MSMC system is described elsewhere1). Patients who were referred to colposcopy following abnormal screening test (Pap or HPV DNA test) according to the standard of care were enrolled. Multi-spectral image sets of the cervix were acquired, consisting of images from the various wavelengths. Image acquisition took 1-2 sec. Areas suspected for dysplasia under white light imaging were biopsied, according to the standard of care. Biopsied sites were recorded on a clockface map of the cervix. Following the procedure, MSMC data was processed from the sites of biopsied sites. To date, the initial histopathological results are still outstanding. Qualitatively, structures in the cervical images were sharper at lower wavelengths than higher wavelengths. Patients tolerated imaging well. The result suggests MSMC holds promise for cervical imaging.

Original languageEnglish
Title of host publicationOptics and Biophotonics in Low-Resource Settings II
EditorsDavid Erickson, David Levitz, Aydogan Ozcan
ISBN (Electronic)9781628419337
StatePublished - 2016
Externally publishedYes
EventOptics and Biophotonics in Low-Resource Settings II - San Francisco, United States
Duration: 13 Feb 201614 Feb 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceOptics and Biophotonics in Low-Resource Settings II
Country/TerritoryUnited States
CitySan Francisco


  • Low resource settings
  • colposcopy
  • multi-spectral imaging
  • translational research


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