TY - JOUR
T1 - Inhibition of protein synthesis by glutathione disulfide in the presence of glutathione
AU - Kosower, Nechama S.
AU - Vanderhoff, Grace A.
AU - Benerofe, Barry
AU - Hunt, Tim
AU - Kosower, Edward M.
PY - 1971/11/5
Y1 - 1971/11/5
N2 - As little as 5 × 10-5 M glutathione disulfide (GSSG) in the presence of 80 × 10-5 M glutathione (GSH) in a rabbit reticulocyte lysate caused a profound inhibition of initiation of protein synthesis. A potential physiological regulatory role for GSSG in protein synthesis is thus revealed.
AB - As little as 5 × 10-5 M glutathione disulfide (GSSG) in the presence of 80 × 10-5 M glutathione (GSH) in a rabbit reticulocyte lysate caused a profound inhibition of initiation of protein synthesis. A potential physiological regulatory role for GSSG in protein synthesis is thus revealed.
UR - http://www.scopus.com/inward/record.url?scp=0015212073&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(71)90490-6
DO - 10.1016/0006-291X(71)90490-6
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AN - SCOPUS:0015212073
SN - 0006-291X
VL - 45
SP - 816
EP - 821
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -