Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice.

Ora Burger, Ervin Weiss, Nathan Sharon, Mina Tabak, Ishak Neeman, Itzhak Ofek

Research output: Contribution to journalComment/debate

Abstract

A high-molecular-weight constituent of cranberry juice has been found to inhibit the sialyllactose specific adhesion of Helicobacter pylori strains to immobilized human mucus, erythrocytes, and cultured gastric epithelial cells. Different isolates of H. pylori differ in their affinity to the cranberry juice constituent. Cranberry juice may also inhibit adhesion of bacteria to the stomach in vivo, and may prove useful for the prevention of stomach ulcer that is caused by H. pylori.

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalCritical Reviews in Food Science and Nutrition
Volume42
Issue number3 Suppl
DOIs
StatePublished - 2002

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