Inhibition of bacterial growth in Vitro by human ejaculate seminal plasma fraction 1 and its possible practical use in male infertility phenomenon

Zvi H. Marcus, Laurence M. Lewin, Raul Ginsberg

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2 Scopus citations

Abstract

Purpose: The in vitro bacteriostatic effect on bacteria by a fraction of human ejaculate (HuSePl-Fr1) was studied. Method: As bacterial indicators, Pseudomonas aeruginosa (Pa), total coliforms (Tc), fecal coliforms (Fc), Escherichia coli (Ec), and Staphylococcus aureus (Sa) were used. These bacterial strains are known as agents that cause urinary and sexually transmitted infections (STI). Results: Preliminary results suggest that HuSePl-Fr1 has a significant in vitro bacteriostatic effect on Pa and Sa at 42°C. In addition, Pa was inhibited at 37°C after 48 hr incubation. The remaining bacterial indicators were not affected. Conclusion: The results indicate a possible protective role of HuSePl-Fr1 in treatment of infertile men due to genital infections.

Original languageEnglish
Pages (from-to)443-446
Number of pages4
JournalJournal of Assisted Reproduction and Genetics
Volume12
Issue number7
DOIs
StatePublished - Aug 1995

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