Inhibition of adherence of Candida albicans to acrylic by a chitin derivative

E. Segal; I. Kremer; D. Dayan

doi:10.1007/BF00158567

Inhibition of adherence of Candida albicans to acrylic by a chitin derivative

E. Segal^*, I. Kremer, D. Dayan

^*Corresponding author for this work

Tel Aviv University

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The purpose of this study was to assess the effect of a chitin derivative (CSE) on the adherence of Candida albicans to acrylic. Fungal adherence to acrylic dentures is considered an essential step in the development of denture stomatitis. Adherence of C. albicans to acrylic pieces (5 × 5mm) was assessed microscopically using a calibrated ocular objective and expressed as number of adherent yeasts/mm² of acrylic. CSE was prepared from commercial chitin (crab shell) and from chitin isolated from C. albicans blastospores. The effect of both CSE types on the adherence of C. albicans to acrylic was examined in two experimental systems: CSE present during the adherence assay and acrylic pieces pretreated with CSE prior to the assay. Both CSE types exerted a significant inhibitory effect when tested in the two experimental systems. These findings are significant for possible prevention of denture stomatitis.

Original language	English
Pages (from-to)	350-355
Number of pages	6
Journal	European Journal of Epidemiology
Volume	8
Issue number	3
DOIs	https://doi.org/10.1007/BF00158567
State	Published - May 1992

Keywords

Acrylic
Adherence
Candida

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10.1007/BF00158567

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abstract = "The purpose of this study was to assess the effect of a chitin derivative (CSE) on the adherence of Candida albicans to acrylic. Fungal adherence to acrylic dentures is considered an essential step in the development of denture stomatitis. Adherence of C. albicans to acrylic pieces (5 × 5mm) was assessed microscopically using a calibrated ocular objective and expressed as number of adherent yeasts/mm2 of acrylic. CSE was prepared from commercial chitin (crab shell) and from chitin isolated from C. albicans blastospores. The effect of both CSE types on the adherence of C. albicans to acrylic was examined in two experimental systems: CSE present during the adherence assay and acrylic pieces pretreated with CSE prior to the assay. Both CSE types exerted a significant inhibitory effect when tested in the two experimental systems. These findings are significant for possible prevention of denture stomatitis.",

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Inhibition of adherence of Candida albicans to acrylic by a chitin derivative

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