Influenza A/H1N1 virus - Old and new

Moran Bodas*, Nadav Davidovich, Ran D. Balicer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Swine influenza is a disease known since 1918. Four decades later, scientists were already isolating the disease-causing agent and learning more about its ability to infect humans. Generally, swine influenza viruses, similarly to avian influenza viruses, do not easily infect humans however, the viruses' ability to undergo substantial genetic re-assortment enhances the emergence of novel influenza viruses, better capable of infecting and transmitting between humans. Pigs also form good mixing vessels for human and avian origin influenza viruses, enabling the emergence of highly virulent influenza strains. Human infection with swine influenza has been recorded in the past, both as sporadic infections and as outbreaks. The best known human swine influenza outbreak took place in Fort Dix (USA) in 1976, concluding in the immunization of almost 45 million U.S. citizens, in a highly controversial immunization program. The current H1N1 (S-OIV) Influenza outbreak was declared by the WHO as an influenza pandemic, setting to rest the lately popular question when will the next pandemic occur? and laying the foundations for the evaluation of preparedness plans. There is great importance in data collection and subsequent updating of current procedures and doctrines.

Original languageEnglish
Pages (from-to)490-494
Number of pages5
Issue number8
StatePublished - Aug 2009


  • Fort dix influenza outbreak (1976)
  • H1N1
  • Influenza pandemic
  • S-OIV (Swine-Origin Influenza Virus)
  • Swine influenza


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