Influence of mechanical tail-detachment techniques of schistosome cercariae on the production, viability, and infectivity of resultant schistosomula: A comparative study

D. Gold*, E. Flescher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Two decaudation methods used by Schistosoma mansoni cercariae for the production of schistosomula by in vitro transformation were comparatively tested. Both low-pressure syringe passage and vortex mixing of the cercariae produced schistosomula of similar percentages of viability, and the levels of worm recovery following subcutaneous injection in mice were also comparable, though low. By all criteria tested, including simplicity and time requirement, the two methods are equally efficient and are well applicable for mass production of schistosomula.

Original languageEnglish
Pages (from-to)570-572
Number of pages3
JournalParasitology Research
Volume86
Issue number7
DOIs
StatePublished - 2000

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