TY - JOUR
T1 - Inflammatory bowel disease and sclerosing cholangitis with ulcerative lesions on skin and soft palate
AU - Fishman, Gadi
AU - Derowe, Ari
AU - Wasserman, Dror
AU - Leider-Trejo, Lionora
AU - Reif, Shimon
PY - 2004/10
Y1 - 2004/10
N2 - Described is a 15-year-old boy who presented with an ulcerative destructive soft palate lesion, skin lesions, and prolonged history of weakness and abdominal pain associated with abnormal liver functions.A midline destructive lesion was considered. However biopsies revealed chronic inflammation. After thorough investigation including colon, liver, skin and uvular biopsies a diagnosis of Inflammatory Bowel Disease in association of Autoimmune Sclerosing Cholangitis was made. Treatment with steroids improved his symptoms, normalized liver functions and enhanced healing of the skin and palatal lesions.This case demonstrates the involvement of the palate in a rare systemic disease and to our knowledge is the first description of Sclerosing Cholangitis presenting as an ulcerative lesion of the soft palate.
AB - Described is a 15-year-old boy who presented with an ulcerative destructive soft palate lesion, skin lesions, and prolonged history of weakness and abdominal pain associated with abnormal liver functions.A midline destructive lesion was considered. However biopsies revealed chronic inflammation. After thorough investigation including colon, liver, skin and uvular biopsies a diagnosis of Inflammatory Bowel Disease in association of Autoimmune Sclerosing Cholangitis was made. Treatment with steroids improved his symptoms, normalized liver functions and enhanced healing of the skin and palatal lesions.This case demonstrates the involvement of the palate in a rare systemic disease and to our knowledge is the first description of Sclerosing Cholangitis presenting as an ulcerative lesion of the soft palate.
KW - Inflammatory bowel disease
KW - Oral ulcer
KW - Sclerosing cholangitis
UR - http://www.scopus.com/inward/record.url?scp=4544232897&partnerID=8YFLogxK
U2 - 10.1016/j.ijporl.2004.04.031
DO - 10.1016/j.ijporl.2004.04.031
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C2 - 15364509
AN - SCOPUS:4544232897
SN - 0165-5876
VL - 68
SP - 1349
EP - 1352
JO - International Journal of Pediatric Otorhinolaryngology
JF - International Journal of Pediatric Otorhinolaryngology
IS - 10
ER -