Inflammatory bowel disease and sclerosing cholangitis with ulcerative lesions on skin and soft palate

Gadi Fishman, Ari Derowe, Dror Wasserman, Lionora Leider-Trejo, Shimon Reif

Research output: Contribution to journalArticlepeer-review

Abstract

Described is a 15-year-old boy who presented with an ulcerative destructive soft palate lesion, skin lesions, and prolonged history of weakness and abdominal pain associated with abnormal liver functions.A midline destructive lesion was considered. However biopsies revealed chronic inflammation. After thorough investigation including colon, liver, skin and uvular biopsies a diagnosis of Inflammatory Bowel Disease in association of Autoimmune Sclerosing Cholangitis was made. Treatment with steroids improved his symptoms, normalized liver functions and enhanced healing of the skin and palatal lesions.This case demonstrates the involvement of the palate in a rare systemic disease and to our knowledge is the first description of Sclerosing Cholangitis presenting as an ulcerative lesion of the soft palate.

Original languageEnglish
Pages (from-to)1349-1352
Number of pages4
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume68
Issue number10
DOIs
StatePublished - Oct 2004
Externally publishedYes

Keywords

  • Inflammatory bowel disease
  • Oral ulcer
  • Sclerosing cholangitis

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