Induction of murine macrophage fungal killing by interleukin 3

I. Bleiberg, Y. Kletter, I. Riklis, I. Fabian

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of recombinant interleukin 3 (IL-3) on the function of murine resident peritoneal macrophages was investigated. IL-3 enhanced the phagocytosis of Candida pseudotropicalis and Candida albicans and enhanced killing of the former. The enhanced killing is inhibited by scavengers of oxygen radicals, suggesting that IL-3 primes macrophages for enhanced oxidative metabolism in response to Candida.

Original languageEnglish
Pages (from-to)895-897
Number of pages3
JournalExperimental Hematology
Volume17
Issue number8
StatePublished - 1989

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