Abstract
The effect of recombinant interleukin 3 (IL-3) on the function of murine resident peritoneal macrophages was investigated. IL-3 enhanced the phagocytosis of Candida pseudotropicalis and Candida albicans and enhanced killing of the former. The enhanced killing is inhibited by scavengers of oxygen radicals, suggesting that IL-3 primes macrophages for enhanced oxidative metabolism in response to Candida.
Original language | English |
---|---|
Pages (from-to) | 895-897 |
Number of pages | 3 |
Journal | Experimental Hematology |
Volume | 17 |
Issue number | 8 |
State | Published - 1989 |