Induction of artificial endometrial cycles with oestradiol implants and injectable progesterone: Establishment of a viable pregnancy in a woman with 17-a-hydroxylase deficiency

Repeated attempts with oral oestrogens and injectable progesterone failed to induce secretory endometrium in a woman with 17-α-hydroxylase deficiency. The insertion of s.c. 17-β-oestradiol implants dramatically improved the endometrial response and enabled the establishment of endometrial maturation. A viable pregnancy was achieved after the uterine transfer of in-vitro fertilized donated eggs.