Individually addressable multi-chamber electroporation platform with dielectrophoresis-assisted cell positioning

Sinwook Park, Gilad Yossifon

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We developed a multifunctional microfluidic platform which integrates electroporation and dielectrophoretic (DEP) trapping/positioning mechanisms. Its feasibility was demonstrated by characterizing and optimizing electroporation efficiency using on-chip spatial gradient of electroporation parameters. For simplicity, human dermal fibroblasts cells with a membrane impermeable fluorescent dye, PI, were used as to indicate electroporation. The results clearly show that the developed microfluidic platform has the potential to achieve high-throughput screening for electroporation with spatial control and uniformity.

Original languageEnglish
Title of host publicationMEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages268-271
Number of pages4
ISBN (Print)9781479935086
DOIs
StatePublished - 2014
Externally publishedYes
Event27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014 - San Francisco, CA, United States
Duration: 26 Jan 201430 Jan 2014

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Conference

Conference27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014
Country/TerritoryUnited States
CitySan Francisco, CA
Period26/01/1430/01/14

Fingerprint

Dive into the research topics of 'Individually addressable multi-chamber electroporation platform with dielectrophoresis-assisted cell positioning'. Together they form a unique fingerprint.

Cite this